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A769662

10 mg

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Cat No. 46-D13

Availability: In stock

$99.00

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All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

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Description

A769662 is a potent and reversible small molecule that activates AMP-activated protein kinase (AMPK). The activation of AMPK inhibits mTOR (mammalian target of rapamycin) signaling, which is a positive effector of cell growth, proliferation and survival. A769662 has been shown to inhibit the Na⁺K⁺-ATPase at higher concentrations. It also inhibits the differentiation of adipocytes.

A769662

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TECHNICAL INFORMATION

 Other Names: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxyl[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile

Chemical Formula:  C20H12N2O3S

CAS Number: 844499-71-4

Molecular Weight: 360.39

Purity:  >98%

Appearance: White Powder

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

For a 10mM concentrated stock solution, reconstitute the compound by adding 2775 µl of DMSO to the entire contents of the vial. For most cells, the maximum tolerance to DMSO is <0.5%.   

 

References

 

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