Other Names: 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide
Chemical Formula: C22H16N4O3
CAS Number: 301836-41-9
Molecular Weight: 384.39
Appearance: A crystalline solid
Solubility: DMSO, Ethanol
Working Concentration: 2µM
STORAGE AND HANDLING
Storage: Store at 4°C and protected from light. Following reconstitution, store aliquots at -20°C.
Stability: Stock solutions stable at -20°C for up to 2 years.
Shipping Conditions: Shipped at room temperature.
Soluble in DMSO (20mg/ml). Soluble in ethanol (2mg/ml). Incubate in a 37°C water bath for 5 minutes if precipitate is observed.
Inman G et al. (2002). SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7. Mol Pharmacol 62(1):65-74.
Laping N et al. (2002). Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542. Mol Pharmacol. 62(1):58-64.