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EHNA Hydrochloride

10 mg

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Cat No. 23-F18

Availability: In stock

$69.00

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All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

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Description

EHNA Hydrochloride is a reversible adenosine deaminase inhibitor that selectively inhibits the cGMP-specific phosphodieterase (PDE2). At a 10µM concentration, EHNA has been shown to effectively and reversibly block the differentiation and maintain the pluripotency of the hES cell line SA121 in feeder- free cultures without exogenously added FGF for up to 30 passages. EHNA has also been used to study the cardioprotective and neuroprotective efforts during ischemia and in the study of cAMP/cGMP signaling.


 

EHNA Hydrochloride

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TECHNICAL INFORMATION

Other Names: 6-​amino-​b-​hexyl-​a-​methyl-​9H-​purine-​9-​ethanol,​ dihydrochloride

Chemical Formula: C14H23N5O • HCl

CAS Number: 58337-38-5

Molecular Weight: 313.8

Purity:  >98%

Appearance:  a crystalline solid  

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. If precipitate is observed,  vortex for 5 minutes. For most cells, the maximum tolerance to DMSO is less than 0.5%. 

 

References

 

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