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Iniparib

10 mg

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Cat No. 63-T21

Availability: In stock

$99.00

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Description

Iniparib is a potent inhibitor of poly (ADP-ribose) polymerase-1 (PARP1). PARP1 has been shown to play an important role in the repair of naturally occurring DNA damage in cells and in DNA that has been damaged by chemotherapy.  Iniparib has demonstrated activity in multiple types of solid tumors, with prolonged inhibition of its target.

Iniparib

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TECHNICAL INFORMATION

Other Names: BSI-201, IND-71677, 4-Iodo-3-nitrobenzamide

Chemical Formula: C7H5IN2O3

CAS Number: 160003-66-7

Molecular Weight: 292.03

Purity:  >98%

Appearance:  a crystalline solid  

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO at 200 mg/ml. If precipitate is observed,  vortex for 5 minutes. For most cells, the maximum tolerance to DMSO is less than 0.5%.

 

References

 

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