Reagents Direct

direct results now

Skip to Main Content »

Your shopping cart is empty

RG108

10 mg

Be the first to review this product

Cat No. 41-L99

Availability: In stock

$99.00

Bulk Quantities Available

All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

OR

Description

RG108 is a potent and specific DNA methyltransferase (DNMT) inhibitor. It causes demethylation and reactivation of tumor suppressor genes and can be used to enhance reprogramming. RG108 has been found to inhibit human tumor cell line proliferation and increases doubling time in culture.

RG108

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

  • RG108

Details

TECHNICAL INFORMATION

 Other Names: 2-(1,3-Dioxo-1,3-dihydro- 2H-isoindol-2-yl)- 3-(1H-indol-3-yl)propionic acid, N-Phthalyl-L-tryptophan

Chemical Formula: C19H14N2O4

CAS Number: 48208-26-0

PubChem Substance ID: 24724594

Molecular Weight:  334.44

Purity:  ≥98% by HPLC

Appearance: yellow solid

Solubility: DMSO >10 mg/ml

IC50 : 115nM

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

RG108 is soluble in DMSO. For a 10mM concentrated stock solution, reconstitute by adding 2990µl of DMSO to the contents of the vial. For most cells, the maximum tolerance to DMSO is less than 0.5%.

 

 

 

 

References

 

Tech Docs