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SU6656

5mg

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Cat No. 42-K78

Availability: In stock

$99.00

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All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

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Description

SU6656 is a potent, cell-permeable, reversible, and ATP-competitive Src family kinase inhibitor. Src kinases are known to function in signal transduction pathways. It inhibits Src as well as other closely related kinases including Fyn, Yes, and Lyn. It can act as a weak inhibitor of Lck and PDGF receptor kinase.

SU6656

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TECHNICAL INFORMATION

Other Names: 2,3-dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide

Chemical Formula: C19H21N3O3S

CAS Number: 330161-87-0

Molecular Weight: 371.5

Purity: >98%

IC50= Src: 280nM, Fyn: 170nM, Yes: 20nM, Lyn: 130nM, Lck: 130nM, PDGF: >10┬ÁM

Appearance: Orange Crystalline Solid

Solubility: DMSO (100mM)

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. Soluble at 12mg/ml

 

References

 

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