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CI-994

10 mg

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Cat No. 46-F92

Availability: In stock

$75.00

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Description

CI-994 is a histone deacetylase (HDAC) inhibitor that induces hyperacetylation in living cells.  CI-994 mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo.  CI-994 originally was developed as an anticonvulsant agent and later was reported to have antitumor activity.


 

CI-994

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TECHNICAL INFORMATION

Other Names: Acetyldinaline, Goe 5549, Gö 5549. PD 123654, Tacedinaline

Chemical Formula:  C15H15N3O2

CAS Number: 112522-64-2

Molecular Weight: 269.30

Purity:  >98%

Appearance:  a crystalline solid 

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO at 66 mg/ml. If precipitate is observed,  vortex for 5 minutes. For most cells, the maximum tolerance to DMSO is less than 0.5%.

 

References

 

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