Reagents Direct

direct results now

Skip to Main Content »

Your shopping cart is empty

Honokiol

10mg

Be the first to review this product

Cat No. 37-R66

Availability: In stock

$109.00

Bulk Quantities Available

All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

OR

Description

Honokiol is a biologically active constituent of oriental medicinal herb Magnolia officinalis/grandiflora. It displays anxiolytic, antithrombotic, anti-tumor properties.  In addition it modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.

Honokiol

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Details

TECHNICAL INFORMATION

Other Names: 5,3’-Diallyl-2,4’-dihydroxydipehenyl, VEGFR tyrosine kinase inhibitor XIX, VEGFR2 kinase inhibitor XV

Chemical Formula: C18H18O2

CAS Number: 35354-74-6

Molecular Weight: 266.3

Purity: >98%

IC50= 0.5 & 11 nM

Appearance: White Solid

Solubility: DMSO (100mM)

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO.

 

References

 

Tech Docs