Other Names: MS-27-275, MS 275-27, Histone Deacetylase Inhibitor I, SNDX-275, Entinostat
Chemical Formula: C21H20N4O3
CAS Number: 209783-80-2
Molecular Weight: 376.41
Appearance: a crystalline solid
STORAGE AND HANDLING
Storage: Store at 4°C and protected from light. Following reconstitution, store aliquots at -20°C.
Stability: Stock solutions stable at -20°C for up to 2 years.
Shipping Conditions: Shipped at room temperature.
Soluble in DMSO at 25 mg/ml with slight warming. If precipitate is observed, vortex for 5 minutes. For most cells, the maximum tolerance to DMSO is less than 0.5%.
Kato et al. (2007) Synergistic in vivo antitumor effect of the histone deacetylase inhibitor MS-275 in combination with interleukin 2 in a murine model of renal cell carcinoma. Clin Cancer Res. 13(15):4538-46.