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Forskolin

10 mg

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Cat No. 86-G99

Availability: In stock

$119.00

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All Reagents Direct products are for laboratory research use only at a qualified research institution, and are not for private individual, patient nor veterinary use.

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Description

Forskolin is a cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Cyclic AMP is a signaling molecule and key regulator of critical enzymes in cellular processes.  Forskolin has also been shown to effect calcium currents and inhibit MAP kinase.


 

Forskolin

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TECHNICAL INFORMATION

Other Names: Colforsin

Chemical Formula: C22H34O7

CAS Number: 6575-29-9

Molecular Weight: 410.50

Purity:  >98%

Appearance:  a crystalline solid  

Solubility: DMSO

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. For a 10mM concentrated stock solution, reconstitute the compound by adding 2.44 ml of DMSO to the entire contents of the vial. . If precipitate is observed,  vortex for 5 minutes. For most cells, the maximum tolerance to DMSO is less than 0.5%. 

 

References

 

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