Other Names: 1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio] butadiene
Chemical Formula: C18H16N6S2
CAS Number: 109511-58-2
Molecular Weight: 380.49
Purity: 99% pure
Appearance: White solid
Melting Point: 156°- 159°C
STORAGE AND HANDLING
Storage: Store at 4°C and protected from light. Following reconstitution, store aliquots at -20°C.
Stability: Stock solutions stable at -20°C for up to 2 years.
Shipping Conditions: Shipped at room temperature.
Soluble in DMSO at 200mg/ml. U0126 is very poorly soluble in ethanol and water. The maximum solubility in water is estimated to be 10-50µl.
Steinberg R et al. (2007). A protein kinase Cepsilion-anti-apoptotic kinase signaling complex protects human vascular endothelial cells against apoptosis through induction of Bcl-2. J Biol Chem. 282 (44):32288-97.