Reagents Direct

direct results now

Skip to Main Content »

Your shopping cart is empty


What's a Small Molecule?

A small molecule is a fast working compound that has an effect on protein function. Small molecules can function across a variety of cell types and species and show great potential for use in therapeutics. Small molecules are unique in that they can inhibit a specific function of a multifunctional protein. They can also disrupt protein-protein interactions. Small molecules are also useful in that they can often be reversed or turned off if needed.

One of the keys to the effectiveness of a small molecule is its purity. You can compare our small molecules to our competitors. The formula is the same. The structure is the same. The molecular weight is the same. Our purity is the same or better. Our molecules look the same, feel the same and work the same or better...all at a more attractive price. Order today at Reagents Direct and take the next step in your research. Order now and your order can be shipped out today!

Sign Up for Discounts

Items 1 to 50 of 71 total

per page
  1. 1
  2. 2

List  Grid 

Set Descending Direction
  1. 17-AAG

    Regular Price: $99.00

    Special Price: $10.00

    17-AAG is a synthetic derivative of geldanamycin and acts as an anti-tumor agent. 17-AAG binds specifically to heat shock protein Hsp90. Hsp90 is a protein chaperone that binds to client proteins. Client proteins include important cancer– relevant targets such as mutated p53, Her2, Bcr-Abl, Raf-1, Akt and others. 17-AAG disrupts the Hsp-900 client protein complexes and leads to the degredation of the client proteins. 


    Learn More
  2. Abiraterone

    Abiraterone is a potent steroidal inhibitor of cytochrome P450 CYP17 with an IC50 at 4 nM. Abiraterone has been shown to selectively inhibit the target enzyme, resulting in inhibition of testosterone production in both the adrenals and the testes.


    Learn More
  3. AT13387

    AT13387 is a synthetic, small-molecule inhibitor of heat shock protein 90 (Hsp90). It selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Hsp90, a chaperone protein upregulated in a variety of tumor cells, regulates the folding, stability and degradation of many oncogenic signaling proteins. Learn More
  4. AT9283

    AT9283 is a multi-targeted kinase inhibitor of both Aurora kinases (A & B) as well as Janus kinase (Jak) 2. It also targets serine/threonine protein kinases associated with myeloid cell proliferation. AT9283 inhibited growth and survival of multiple solid tumor cell lines. Learn More
  5. AZD1480

    AZD1480 is a potent JAK2 inhibitor that can suppress growth, survival, as well as FGFR3 and STAT3 signaling and downstream targets. AZD1480 is a potent, competitive small-molecule inhibitor of JAK1/2 kinase, and is capable of inhibiting STAT3 phosphorylation and tumor growth in a STAT3-dependent manner. This may lead to induction of tumor cell apoptosis and a decrease in cellular proliferation. JAK2, often upregulated or mutated in a variety of cancer cells, mediates STAT3 activation and plays a key role in tumor cell proliferation and survival. Learn More
  6. Bafilomycin A1
    Bafilomycin A1

    Bafilomycin A1 is a macrolide antibiotic that selectively inhibits vacuolar-type (v-type) H+ ATPase. The compound can inhibit E1E2 ATPases from sarcoplasmic reticulum, E. coli, and ox brain versus F1F0 ATPases found in bacteria and mitochondria. It blocks pH regulation in brain cells. Additionally, Bafilomycin A1 prevents lysosomal cholesterol trafficking in macrophages and can be used to distinguish different types of ATPases. Learn More
  7. BAY 11-7082
    BAY 11-7082

    Bay 11-7082 is an inhibitor of cytokine-induced IκB-α phosphorylation. The transcription factor NF-κB plays a key role in regulating over 150 target genes that include the expression of inflammatory cytokines, chemokines, immunoreceptors, and cell adhesion molecules.  Bay 11-7082 selective and irreversibly inhibits NF-κB activation by blocking TNF-α-induced phosphorylation of IκB-α without affecting IκB-α phosphorylation.  BAY 11-7082 has also demonstrated stimulation of the stress-activated protein kinases, p38 and JNK-1.


    Learn More
  8. BEZ235 (NPV-BEZ235)
    BEZ235 (NPV-BEZ235)

    NPV-BEZ235 is a dual inhibitor of phosphatidylinositol 3-kinase (P13K)and the downstream mammalian target of rapamycin (mTOR) by binding to the ATP-binding cleft of these enzymes. It specifically blocks the dysfunctional activation of the P13K pathway and induce G(1) arrest. NPV-BEZ235 has been shown to inhibit VEGF induced cell proliferation and survival in vitro and VEGF induced angiogenesis in vivo. It has also been shown to inhibit the growth of human cancer in animal models.


    Learn More
  9. BI2536

    BI2536 is a small molecule inhibitor of Polo Like Kinase 1 (PLK1). PLK1 is a serine/threonine protein kinase and is a key regulator of multiple processes essential to mitosis and cell division. Inhibition of PLK1 by BI2536 results in mitotic arrest, disruption of cytokinesis and apoptosis in tumor cell populations.  BI2536 has been shown to inhibit growth of xenographs in nude mice and induces regression of large tumors with well tolerated intravenous dose regimens.


    Learn More
  10. BIBW-2992

    BIBW-2992 is a irreversible and dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) kinases.  The potency of BIBW-2992 on the EGFR and HER2 kinases revealed IC₅₀ values of 0.5 nM and 14 nM, respectively. BIBW-2992 is highly selective for these kinases and no additional inhibition of other kinases has been observed. BIBW-2992 has also been shown to suppress EGF-induced EGFR phosphorylation and cellular proliferation in various cell lines.

    Learn More
  11. Brefeldin A
    Brefeldin A

    Brefeldin A (BFA) (IC50 value of 0.2 μM) is an inhibitor of ATPase. ATPase is a chemical enzyme. It is essential in the ADP/ATP exchange providing chemical potential energy. ATP supplies the energy for such physiological activities such as importing metabolites necessary for cell metabolism, exporting toxins, wastes, and solutes that can hinder cellular processes, cell proliferation, ER stress and so forth. When tested with cell line HEK293 cells (stably express wild-type (wt) CRELD2), BFA treatment nearly abolished the secretion of wtCRELD2 completely via inhibiting the transportation of proteins from the ER to the Golgi apparatus [4]. In MCF-7 cells and Hela cells, treatment with BFA induced p53 expression via inhibiting ATP which enhanced ER stress [5]. When treated with colorectal cancer cell line HCT116 cells, BFA treatment induced cells apoprosis by inhibiting ATP which functioned in the process of cellular vesicle trafficking Treatment with BFA could attenuate stimulus-dependent hyperalgesia phenomenon via inhibiting vesicular exocytosis which process is important for ATP release. BFA also is reported as an inhibitor for GTP/GDP exchange in a dose-dependent way, which is important in vesicular trafficking. Learn More
  12. CH5424802

    CH5424802, also known as AF802, is a potent and selective Anaplastic lymphoma kinase (ALK) inhibitor. ALK is a tyrosine kinase that is constitutively activated in certain cancers, following gene alterations such as chromosomal translocation, amplification, or point mutation. It has shown limited inhibition of other kinases, GAK and LTK. LTK is known to show greatest sequence similarity to ALK. Learn More
  13. CI-994

    CI-994 is a histone deacetylase (HDAC) inhibitor that induces hyperacetylation in living cells.  CI-994 mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo.  CI-994 originally was developed as an anticonvulsant agent and later was reported to have antitumor activity.


    Learn More
  14. Crizotinib

    Crizotinib is a potent ATP competitive inhibitor of c-MET and anaplastic lymphoma kinase (ALK). It has been shown to display antitumor efficacy in multiple tumor models and has been shown to inhibit c-MET dependent proliferation, migration and invasion of tumor cells in vitro. Crizotinib is selective for c-MET and ALK against over 120 different kinases. 

    Learn More
  15. Cyclopamine

    Cyclopamine is a small molecule inhibitor of the sonic hedgehog pathway (Hh) by binding to the heptahelical bundle of Smoothened. It inhibits the growth of medulloblastoma cells. Hedgehog signaling is involved in embryogenesis as well as cancer progression. It is a steroid alkaloid  and originally identified as a teratogenic agent.


    Learn More
  16. Dacomitinib

    Dacomitinib, also known as PF-00299804, is a second-generation irreversible pan-erbB (HER) receptor tyrosine kinase inhibitor.  It is believed to irreversibly inhibit erbB tyrosine kinase activity through binding at the ATP site and covalent modification of nucleophilic cysteine residues in the catalytic domains of erbB family members.  The HER family of tyrosine kinases included receptors HER-1 (EGFR), HER-2,3 and 4.  The HER signaling pathway plays a role in the normal regulation of cell growth and proliferation, differentiation, and apoptosis.  Activation of HER receptors drives signal transduction pathways; dysregulated signaling through the HER receptors may lead to malignant transformation and growth. Learn More
  17. Daidzin

    Daidzin is a glucoside of the isoflavone daidzein found in soy beans. It demonstrates chemopreventive activities by inhibiting the bioactivation of carcinogenic arylamines. It is also a potent, selective inhibitor of human mitochondrial aldehyde dehydrogenase. Learn More
  18. Dorsomorphin Chemical Structure

    Regular Price: $99.00

    Special Price: $59.00

    Dorsomorphin (also known as Compound C) is a potent, reversible, AMPK inhibitor with Ki of 109 NM in the absence of AMP. In addition, it has been found to selectively inhibit bone morphogenetic protein (BMP) signaling. Learn More
  19. Dovitinib

    Dovitinib is a small molecule receptor tyrosine kinase inhibitor. It potently inhibits receptor tyrosine kinases including FLT3, c-KIT, CSF-1R/c-fms, FGFR1, FGFR3, VEGFR1/Flt1,VEGFR2/Flk1, VEGFR3/Flt4, PDGFRβ, and PDGFRα. Dovitinib shows both antitumor and antiangiogenic activities in vivo. It has also been used as an  effective treatment in xenograft mouse models of FGFR3 multiple myeloma (MM).  

    Learn More
  20. Enzastaurin

    Enzastaurin inhibits PKCβ, PKCα, PKCγ and PKCε with IC50's of 0.006, 0.039, 0.083 and 0.110 µM, respectively. It has a direct effect on human tumor cells by inducing apoptosis and suppressing the proliferation of cultured tumor cells. Enzastaurin suppresses VEGF-induced angiogenesis in the rat corneal micropocket assay and decreases microvessel density. It also prevents VEGF secretion from human tumor cell xenographs in nude mice. Prolonged courses of Enzastaurin increases chemotherapy or radiation tumor growth delay of breast, glioma and small cell lung cancer xenographs.


    Learn More
  21. Everolimus

    Everolimus inhibits mTOR (mammalian target of rapamycin), a serine-threonine kinase, by binding with high affinity to the FK506 binding protein-12 (FKBP-12) thus inducing cell growth arrest and apoptosis. It is chemically very similar to Rapamycin. It is also used to prevent rejection of organ transplants. Learn More
  22. Fludarabine

    Fludarabine, also known as Fludara, F-ara-A, and NSC 118218, is a purine antimetabolite. It's activity occurs as the result of activation to 2-fluoro-ara-ATP and includes inhibition of DNA synthesis primarily in the S-phase of cell division by inhibition of ribonucleotide reductase and the DNA polymerases. It is also postulated that fludarabine interferes with RNA by decreased incorporation of uridine and leucine into RNA and protein, respectively. Fludarabine is also active against non-proliferating cells. Learn More
  23. FTY720

    FTY720 is a potent sphingosine-1-phosphate (S1P) receptors agonist that reverses the effects of BCR-ABL kinase.  It is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5.) FTY720 is a novel immunomodulating agent that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.

    Learn More
  24. GANT 61
    GANT 61

    GANT 61 is a GLI antagonist. It inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GL1 nuclear accumulation. GANT 61 has been shown to inhibit proliferation of PANC1 and 22Rv1 cancer cells in vitro. In Vivo, it has displayed display antiproliferative effects and antitumor activity. GANT 61 has also been shown to block cell growth in vivo xenograft models using human prostate cancer cells.


    Learn More
  25. GDC0449 (Vismodegib)
    GDC0449 (Vismodegib)

    GDC0449 is a potent hedgehog (Hh) signaling pathway inhibitor with an IC₅₀ of 3nM.  The Hedgehog signaling pathway plays an important role in tissue growth and repair. GDC0449 works by blocking the activities of the Hedgehog-ligand cell surface receptors PTCH or SMO and suppresses Hedgehog signaling. It has been shown to inhibit the growth of primary pancreatic xenographs without non-specifically inhibiting pancreatic cell proliferation in vitro. GDC0449 has also been shown to inhibit ABCG2, Pgp, and MRP1-important ABC transporters associated with MDR. It has also been used to treat medullablastoma in animal models.


    Learn More
  26. GDC0941

    GDC0941 is a phosphatidylinositol 3-kinase (P13K) inhibitor. GDC-0941 inhibits the activity of recombinant PI3K in vitro with IC50's of 0.003 µM (P110α), 0.033 µM (P110β), 0.003 µM (P110δ), 0.075 µM (P110γ), 0.58 µM (mTOR) and 1.23 µM (DNA-PK).


    Learn More
  27. Genistein

    Genistein is a naturally occurring isoflavone found mainly in soy products. It inhibits protein tyrosine kinase and topoisomerase-II as well as angiogenesis. It has been shown to be involved in regulating apoptosis, an important target in cancer research. Learn More
  28. GW788388

    GW788388 is a selective inhibitor of transforming growth factor-beta type I (TGF-betaI) receptor (activin receptor-like kinase 5 (ALK5)). It is know to inhibit esophageal squamous cell carcinoma induced neoangiogenisis. Learn More
  29. HA-1077 (dihydrochloride)
    HA-1077 (dihydrochloride)

    HA-1077 is a potent inhibitor of Rho-associated kinase II (ROCK-II), and also inhibits Protein Kinase C-related kinase 2 (PRK2),  Mitogen- and Stress-Activated Protein Kinase (MSK1), and Mitogen Activated Protein Kinase-Activated Protein Kinase 1b (MAPKAP-K1b). HA-1077 is a novel vasodilator agent which inhibits vascular smooth muscle contraction by acting as an intracellular Ca2+ antagonist. Through the inhibition of Rho-kinase, HA-1077 has been shown to reduce blood vessel constriction, decrease pulmonary arterial pressure, inhibit tumor angiogenesis, and improve insulin signaling in rodent models.


    Learn More
  30. Honokiol

    Honokiol is a biologically active constituent of oriental medicinal herb Magnolia officinalis/grandiflora. It displays anxiolytic, antithrombotic, anti-tumor properties.  In addition it modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides. Learn More
  31. INCB-018424

    INCB-018424, also known as Ruxolitinib, is a potent and selective inhibitor of Janus -associated kinase 1 and 2 (JAK1,2). It acts by blocking the JAK/STAT pathway. It is also shown to selectively inhibit a wide range of other kinases including JAK3. Learn More
  32. Indolactam V
    Indolactam V

    Indolactam V is an activator of protein kinase C (PKC) that works by inhibiting PKC isozymes (alpha, beta-I, beta-II, gamma, delta, epsilon, eta, theta). This inducing differentiation in embryonic stem cells into pancreatic progenitors. It also exhibits tumor promoting activity. Learn More
  33. Iniparib

    Iniparib is a potent inhibitor of poly (ADP-ribose) polymerase-1 (PARP1). PARP1 has been shown to play an important role in the repair of naturally occurring DNA damage in cells and in DNA that has been damaged by chemotherapy.  Iniparib has demonstrated activity in multiple types of solid tumors, with prolonged inhibition of its target.

    Learn More
  34. IPA3

    IPA3 is a selective inhibitor of P21-activated kinase (PAK1). It functions by targeting the autoregulatroy mechanism, inhibiting the activators from binding to the active sites on the enzyme, producing the inactive conformation of PAKs. The autoinhibitory regions suppress the catalytic activity of its kinase domain, which are removed once activators have bound to the protein. IPA2 does not inhibit PAK1 if activators are already bound to the enzyme. PAK1 is implicated in tumorigenisis and metastasis. Learn More
  35. IWP-2

    IWP-2 is an inhibitor of Wnt production and an inactivator of Porcn function.  The Wnt/b-catenin pathway maintains transcriptional programs that enable stem cells to remain multipotent and hyperactivation of this pathway leads to disease stage. IWP-2 inactivates Porcn function by either directly inhibiting the Porcn active site or by modulating the function of the Porcn regulator.


    Learn More
  36. IWR-1 endo
    IWR-1 endo

    Wnt signaling proteins are small secreted proteins active in embryonic development, tumorigenesis and tissue homeostasis.  IWR-1 endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 of 180nM.  IWR-1 endo inhibits Wnt-induced accumulation of β-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, Ck1, and Gsk3β. IWR-1-endo stabilizes the destruction complex, increasing the level of Axin2 protein without changing the levels of Apc or Gsk3β. In in vivo tests , IWR-1 endo has been shown to inhibit zebrafish tail fin regeneration at a minimum inhibitory concentration of 0.5 µM.

    Learn More
  37. LBH589

    LBH589 (Panobinostat) is a novel HDAC inhibitor that has been shown to induce acetylation of histone H3 and H4, increase p21 levels and disrupt the chaperone function of hsp90. LBH589 induces G(2) M Cell cycle arrest and inhibits HUVEC proliferation and viability. At noncytotoxic concentrations. LBH589 inhibits AKT activity, endothelial tube formation and Matrigel invasion.

    Learn More
  38. Masitinib (AB1010)
    Masitinib (AB1010)

    Masitinib (AB1010) is a protein tyrosine kinase inhibitor. It targets c-KIT, PDGFR and FGFR3.  It also potently inhibits human and murine KIT with activating mutations in the juxtamembrane domain. In vivo, Masitinib  has been shown to block tumor growth in mice with subcutaneous grafts of Ba/F3 cells expressing a juxtamembrane KIT mutant.


    Learn More
  39. MG132

    MG132 is a proteasome inhibitor. Proteasome are found at high concentrations in eukaryotic cells, which causes protein degradation. This inhibitor enhances thermotolerance in a variety of cell types. MG132 also activates JNK-1 which may lead to apoptosis under cell stress. It has been shown to be involved with the cell cycle, in controlling inflammatory processes and gene expression. Learn More
  40. MS-275

    MS-275 is a potent HDAC inhibitor with an IC50 of 0.3 and 8µM for HDAC1 and HDAC3. It has been shown to inhibit tumor growth by inducing tumor suppressors p21WAF1/CIP1 and gelsolin through the acetylation of histones and changing cell cycle distribution. MS-275 has been shown to exert dose-dependent effects in human leukemia cells at low concentrations in human prostate cancer lines. MS-275 inhibits proliferation of various human tumor cell lines and inhibits the growth of human tumor xenographs in the nude mouse.

    Learn More
  41. Neratinib

    Neratinib, also known as HKI-272, is a second-generation inhibitor of the ErbB family of receptor kinases. Neratinib is an irreversible inhibitor of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER-2) tyrosine kinases by targeting a cysteine residue in the ATP-binding site of the receptor.  Neratinib has been shown to inhibit the proliferation of HER-2 overexpressing human breast cancer cell lines and EGFR-dependent cells in vitro. In vivo, Neratinib has been shown to be active against HER-2- and EGFR-dependent tumor xenograft models .


    Learn More
  42. Nilotinib

    Nilotinib, also known as AMN107 or Tasigna, is a tyrosine kinase inhibitor. It is an analog of imatinib with similar multiple kinase targets, but without inhibition of the Src gene. This gene regulates tyrosine kinase proteins that in turn affect whether cells multiply or die. Tyrosine kinase inhibitors interfere with cell communication and growth. Nilotinib is a selective BCR-ABL inhibitor that fits into the ATP-binding site of the BCR-ABL protein. It has a higher affinity for the BCR-ABl protein than imatinib. It is not only more potent than imatinib against wild-type BCR-ABL (IC50 < 30 nM), but also significantly active against 32/33 imatinib-resistant BCR-ABL mutants. Nilotinib was as potent as imatinib in inducing apoptosis (IC50 = 0.54 nM) and inhibiting proliferation (IC50 = 0.20 nM) of EOL-1 cells. Learn More
  43. NKH477

    NKH477 is a water-soluble analog of forskolin. Like forskolin, NKH477 activates adenylyl cyclases without altering the activity of phosphodiesterases or sodium/potassium ATPases. This compound stimulates cardiac (type V) adenylyl cyclase more potently than other isoforms. It dose dependently increases cAMP and blocks potassium-induced contraction concetrations in smooth muscle strips (IC50 = 80 nM). NKH 477 causes relaxation of histamine treated guinea pig smooth muscle (IC50 = 32 nM). Learn More
  44. NSC74589

    NSC74859, also known as S3I-201, binds the Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription, therefore, inhibiting growth and inducing apoptosis preferentially in tumor cells that contain persistently activated Stat3. Moreover, NSC74859 also inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin. Learn More
  45. Nutlin-3

    Nutlin-3 is a MDM2 antagonist, a p53 activator and an apoptosis inducer. MDM2 works by binding the p53 tumor suppressor protein and negatively regulating its transcriptional activity and stability. Inhibition of the MDM-p53 interaction results in the stabilization of p53, cell cycle arrest and apoptosis. Learn More
  46. Olaparib

    Olaparib is a potent small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP). It acts by binding to PARP, inhibiting PARP-mediaed repair of single strand DNA breaks. PARP inhibition may enhance the cytotoxicity of DNA-damaging agents and may reverse tumor cell chemoresistance and radioresistance. PARP catalyzes post-translational ADP-ribosylation of nuclear proteins and can be activated by single-stranded DNA breaks. Learn More
  47. PD98059

    Regular Price: $49.00

    Special Price: $39.00

    PD98059 is a highly selective noncompetitive inhibitor of MEK1 and MEK2. It prevents the activation of MAPKK1 by Raf or MEK kinase with an IC50 of 2-7µM, but does not inhibit Raf-activated MAPKK1.  At concentrations up to 100µM, PD98059 does not inhibit activation of MKK3 or SEK as determined by measuring phosphorylation at its activation site. PD98059 has been shown to inhibit cell growth and proliferation in acute myelogenous leukemia (AML) cell lines and causes G1 arrest by blocking p53-dependent p21 induction.


    Learn More
  48. PLX-4032

    PLX-4032 (AKA Vemurafenib) is a highly selective inhibitor of BRAF kinase activity with an IC₅₀ of 44 nmol/L against V600E-mutant BRAF. BRAFV600E cancer-causing mutation occurs in most melanomas and about eight percent of all solid tumors. PLX-4032 has been shown to selectively inhibit the RAF/MEK/ERK pathway in BRAF mutant cells and induce regression of BRAF mutant xenographs. PLX4032 has also been shown to cause programmed cell death in melanoma cell lines and may be a potential anti-tumor agent.   


    Learn More
  49. Ponatinib

    Ponatinib, also known as AP24534, is considered to be a pan-BCR-ABL inhibitor. It was specifically designed to bind BCR-ABL with very high potency and to inhibit the entire spectrum of mutants conferring resistance against other tyrosine kinase inhibitors (TKIs), such as VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosporylation and LYN among others, including the T315I mutant that is resistant to all current therapies. It has been shown to suppress BCR-ALB(T315I)-driven tumor growth in mice. Learn More
  50. PRE-084

    Out of stock

    PRE-084 is a high affinity sigma receptor agonist, selective for the σ1 subtype. It is a potent ligand of the σ receptor without much affinity for the PCP receptors. Learn More

Items 1 to 50 of 71 total

per page
  1. 1
  2. 2

List  Grid 

Set Descending Direction


High Quality, Validated Reagents

 At Reagents Direct, we strive to supply the highest quality reagents at the best price to your lab. Our products are carefully tested for high purity, and are structurally verified by mass spectometry. We work closely with our validated vendors to get you the best commercially available reagents into your hands and into your lab. We know that there are many other reagent companies out there with these same reagents. We guarantee that our products are equal or better than our competition, and are almost always at a lower cost to your lab. Don't believe us? Give us a try. You will not be disappointed.

Easy and Fast Purchasing Process

At Reagents Direct, we make the purchasing process as easy as possible. Our helpful customer servcie team is always available to help you with your purchasing needs. Need a reagent rushed to your lab? No problem. We send all our orders out overnight, so that you never have to put your experiments on hold while waiting for your reagents. We will even ship your products before we receive a PO# from your purchasing department if needed. Our fast and easy online purchasing system allows you to place an order within minutes, with the confidence that you will always be getting the best reagents available. When we receive your order, we will ship out your products as soon as humanly possible (or as fast as our shipping department can run them to you- which is pretty fast, as they are runners).

In addition to high quality, quick to ship reagents, we are stepping it up another notch and have the best Rewards Program in the business, where you can get 20% of your order back as a gift card to Amazon, iTunes, Starbucks or Reagents Direct. Order now and see your reagents in your lab tomorrow morning, ready to work their magic on your cell culture project.