Genistein

10 mg

Cat. No.: 94-W43

$44.00

Genistein is a naturally occurring isoflavone found mainly in soy products. It inhibits protein tyrosine kinase and topoisomerase-II as well as angiogenesis. It has been shown to be involved in regulating apoptosis, an important target in cancer research.

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TECHNICAL INFORMATION

Other Names: 5,7-dihydroxy-3-(4-hydroxphenyl)-4H-1-benzopyran-4-one

Chemical Formula: C15H10O5

CAS Number: 446-72-0

Molecular Weight: 270.24

Purity: >98%

IC50= 10mL

Appearance: Off white crystalline solidr

Solubility: DMSO (100mM)

 

STORAGE AND HANDLING

Storage: Store at 4°C and protected from light. Following reconstitution, store  aliquots at -20°C. 

Stability: Stock solutions stable at -20°C for up to 2 years.

Shipping Conditions: Shipped at room temperature.

 

PRODUCT USE

Soluble in DMSO. Soluble at 20mg/ml

References

Ghaemi | A. | et al. (2012). Genistein induces a protective immunomodulatory effect in a mouse of cervical cancer. Iran J Immunol. 9:119-27.

Masuda | S. | et al. (2012). Change in mutagenic activity of genistein after a nitrite treatment. Biosci Biotechnol Biochem. 76:938-41.

Al-Nakkash | L. | et al. (2012). Genistein stimulates jejuna chloride secretion via sex-dependent | estrogen receptor or adenylate cyclase mechanisms. Cell Physiol Biochem. 30:137-50.

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